Application and accuracy analysis of three-dimensional transvaginal ultrasound in the diagnosis of endometrial lesions in postmenopausal women

Objectives: To evaluate the value of three-dimensional transvaginal ultrasound (3D-TVS) for endometrial lesions in postmenopausal women, so as to improve the accuracy of clinical diagnosis of endometrial lesions in postmenopausal women.

Methods: A total of 170 female patients admitted to Tianjin Central Hospital of Gynecology and Obstetrics from April 2018 to April 2020 were included in this study. Among them, 110 patients with pathologically confirmed postmenopausal endometrial lesions were divided into the study group (65 patients with benign lesions, 45 patients with malignant lesions), while 60 healthy postmenopausal women were divided into the volunteer group. PASS software was used to calculate the sample size. 3D-TVS was performed in both groups, and the results of the different groups were compared and analyzed.

Results: The pathological results were invoked as the gold standard for detection, and the accuracy, sensitivity and specificity of 3D-TVS were 97.27%, 77.78% and 80% respectively. Patients in the study group had higher endometrial thickness and endometrial volume than those in the volunteer group (p<0.05). The results of ultrasound parameters in the benign lesion group were lower than those in the malignant lesion group (p<0.05), while the vascular index and micro-vessel density in the malignant lesion group were significantly higher than those in the benign lesion group (p<0.05).

Conclusion: 3D-TVS has obvious clinical value in the diagnosis of endometrial lesions in postmenopausal women, boasting a variety of advantages, such as high accuracy, sensitivity and specificity, effectively reflecting the blood flow of patients with endometrial lesions, and further determining the degree of benign and malignant lesions in patients.