Evaluating the Anticancer Properties of Musa acuminata colla Ethanolic Extract through In vitro Analysis

The study examined the possible anticancer properties of a colla pulp extract derived from Musa acuminata. It employed three different cancer cell lines, MDA-MB-231 (breast cancer), HCT-116 (colon cancer), and MG-63 (osteosarcoma). We evaluated the antiproliferative properties using the MTT test and identified the bioactive components through GC-MS analysis. The GC-MS analysis showed that the ethanol extract contained several compounds that could be useful in the fight against cancer. These compounds included palmitic acid, linoleic acid, 5-hydroxymethylfurfural, and 5-Methyl-2-ethylamino-2-thiazoline. The extract showed remarkable cytotoxicity against the cancer cell lines, with IC50 values of 250 µg/ml, 175 µg/ml, and 320 µg/ml for MDA-MB-231, HCT-116, and MG-63 cell lines, respectively. Finally, it was determined that banana pulp contains a significant number of phenolic compounds, provitamin A, and antioxidants. The present study suggests that bananas could have promising uses in the field of cancer research, treatment, and prevention.