Response of Viteline Blood Vessels of Chick Embryo to the Extract of Tridax Procumbens

The objective of this histological study is to evaluate the healing and anti-angiogenic property of the crude leaf extract of T. procumbens. Tridax procumbens (Linn.) is a plant that is widely used as a herbal medicine to stop bleeding and heal wounds. During embryogenesis, angiogenesis plays a crucial function in the development of the embryo. The chick chorioallantoic membrane (CAM) experiment is used to investigate the effect of Tridax procumbens leaf extract in vivo. The present work deals with angiogenesis, anti-angiogenesis and histological study of newly forming vitelline blood vessels. The histological study revealed that the thickening effect of endothelium and the tunica media of vitelline veins is due to leaf extract of Tridax procumbens. The phytochemicals such as essential oils, triterpenoids, alkaloids, flavonoids present in the leaves of this plant could be responding in thickening of blood vessels and ultimately healing process for the purpose of healing.